PHARMACY 421 - Fall 2001
MEDICINAL CHEMISTRY I
CRN 70453 Section 01, 3 credits
Skaggs Building 117
MWF 10:10-11:00
Syllabus for Part I - Prof. C. M. Thompson
The lecture notes are available by following the
blue underlined links marked "(e-notes)" beneath the date. Print the notes directly from the web browser or “save link
as” and print from desktop.
The e-notes and syllabus may not correlate perfectly
as the course progresses - print out e-notes in advance.
The lectures in part 1 will include a large amount
of organic chemistry.
An
excellent review of organic chemistry and organic problem-solving can be found
at:
http://www.cem.msu.edu/~reusch/OrgPage/Crsepage/problems.htm
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Date |
Topic(s) |
Information
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Sept 5 |
Course Guidelines.
Introduction to Medicinal Chemistry |
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Sept 7 |
Introduction to Functional
Groups in Medicinal Chemistry; |
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Sept 10 |
Introduction to Functional
Groups in Medicinal Chemistry |
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Sept 12 |
Physico-chemical
Properties and Metabolic Fate of Functional Groups |
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Sept 14 |
Physico-chemical
Properties and Metabolic Fate of Functional Groups |
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Sept 17 |
Physico-chemical
Properties and Metabolic Fate of Functional Groups |
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Sept 19 |
Physico-chemical
Properties and Metabolic Fate of Functional Groups |
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Sept 21 |
Acid/base review,
equilibrium, pKa |
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Sept 24 |
Acid/base review,
equilibrium, pKa |
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Sept 26 |
Quantitative Structure
Activity Relationships (QSAR) |
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Sept 28 |
Quantitative Structure
Activity Relationships (QSAR) |
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Oct 1 |
Quantitative Structure
Activity Relationships (QSAR) |
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Oct 3 |
Case Histories in
Medicinal Chemistry – Select Examples |
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Oct 5 |
EXAM I |
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Oct 8 |
Professor Freeman begins. |
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